Sample interview questions: Tell us about your knowledge of cell-based models for cardiovascular research.
Sample answer:
-
In vitro models:
- Primary cell cultures: These are cells that have been isolated directly from a tissue or organ and cultured in a лаборатория environment. They retain many of the characteristics of the cells in the original tissue, making them a valuable model for studying cardiovascular function.
- Immortalized cell lines: These are cell lines that have been genetically modified to grow indefinitely in culture. They are often used in research because they are easy to maintain and can be easily manipulated.
- Stem cell-derived cardiomyocytes: These cardiomyocytes are generated from stem cells, such as embryonic stem cells or induced pluripotent stem cells. They can be used to study the development of the heart and to model cardiovascular diseases.
-
In vivo models:
- Animal models: Animal models, such as mice and zebrafish, are used to study cardiovascular function and disease. They allow researchers to study the effects of drugs and treatments in a living organism.
- Organ-on-a-chip models: Organ-on-a-chip models are small devices that mimic the structure and function of a specific organ, such as the heart. They can be used to study the effects of drugs and treatments on the organ in a more physiologically relevant environment.
-
Computational models:
- Mathematic… Read full answer