Sample interview questions: Can you discuss your experience in studying the genetic basis of complex traits using genomics approaches?
Sample answer:
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Experience in studying the genetic basis of complex traits using genomics approaches:
- Conducted genome-wide association studies (GWAS) to identify genetic variants associated with complex traits, such as cancer, cardiovascular disease, and diabetes.
- Performed linkage analysis to map genes responsible for rare Mendelian disorders.
- Utilized next-generation sequencing (NGS) technologies, including whole-genome sequencing (WGS) and RNA sequencing (RNA-seq), to investigate the genetic and molecular mechanisms underlying complex traits.
- Applied bioinformatics tools and statistical methods to analyze large-scale genomics data, including single-nucleotide polymorphisms (SNPs), copy number variations (CNVs), and gene expression profiles.
- Collaborated with clinicians, geneticists, and other researchers to design and execute genomics studies, interpret results, and contribute to the advancement of knowledge in the field of complex trait genetics.
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Skills and expertise:
- Strong foundation in genomics, genetics, bioinformatics, and statistical methods.
- Proficiency in various genomics techniques, including GWAS, linkage analysis, N… Read full answer