Sample interview questions: Can you discuss any experience you have with theoretical biophysics or protein folding?
Sample answer:
Yes, I can discuss my experience with theoretical biophysics and protein folding. In my research career as a physicist, I have had the opportunity to work extensively in the field of theoretical biophysics and specifically on protein folding. Protein folding is a fascinating area of study as it is crucial for understanding the structure and function of proteins, which are the building blocks of life.
One of my notable experiences in theoretical biophysics was working on developing computational models to simulate and predict protein folding pathways. This involved applying principles from statistical mechanics, thermodynamics, and molecular dynamics simulations to understand the forces and interactions that govern protein folding. By studying the folding dynamics of proteins, we aimed to unravel the underlying mechanisms that contribute to protein stability and misfolding, which are often associated with various diseases.
To further enhance my knowledge in this field, I actively engaged in collaborations with experimental biophysicists and biochemists. This interdisciplinary approach allowed me to gain hands-on experience in experimental techniques such as X-ray crystallography, nuclear magnetic resonance (NMR) spectroscopy, and single-molecule fluorescence techniques. By combining experimental data with computational simulations, we were able to refine our model… Read full answer