Have you ever faced challenges in the development and optimization of controlled-release dosage forms? How did you overcome them?

Sample interview questions: Have you ever faced challenges in the development and optimization of controlled-release dosage forms? How did you overcome them?

Sample answer:

  • Challenge: Ensuring uniform drug distribution and release throughout the formulation.

  • Solution: Implemented advanced manufacturing techniques, such as hot-melt granulation or co-extrusion, to achieve uniform drug dispersion and sustained release.

  • Challenge: Optimizing drug release kinetics to meet therapeutic requirements.

  • Solution: Utilized modeling and simulation tools to predict drug release profiles and adjusted formulation parameters, such as polymer type and concentration, to achieve the desired release kinetics.

  • Challenge: Addressing stability and storage issues associated with controlled-release formulations.

  • Solution: Conducted comprehensive stability studies… Read full answer

    Source: https://hireabo.com/job/5_2_16/Pharmaceutical%20Chemist

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