Sample interview questions: Can you explain the concept of combinatorial chemistry and its applications in organic synthesis?
Sample answer:
Combinatorial Chemistry and its Applications in Organic Synthesis
Combinatorial chemistry is a powerful technique that enables the rapid and efficient synthesis of a vast array of compounds. It involves the systematic assembly of libraries of compounds, typically comprising millions or even billions of members, by combining a set of building blocks in all possible combinations.
The applications of combinatorial chemistry in organic synthesis are vielfältig:
- Drug discovery: By creating vast libraries of compounds, combinatorial chemistry accelerates the identification of potential drug candidates. It allows for the rapid screening of multiple compounds against specific biological targets, leading to a streamlined lead optimization process.
- Material science: Combinatorial chemistry facilitates the development of novel materials with tailored properties. It enables the exploration of a wide range of chemical space and the optimization of materials for specific applications, such as electronics, optics, and catalysis.
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