Sample interview questions: Can you discuss your experience with analytical techniques such as chromatography or mass spectrometry in physical chemistry?
Sample answer:
Chromatography
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Expertise in various chromatography techniques, including gas chromatography (GC), high-performance liquid chromatography (HPLC), and ultra-performance liquid chromatography (UPLC).
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Proficient in sample preparation, column selection, and optimization of chromatographic conditions to achieve efficient separation and analysis of complex mixtures.
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Experience in developing and validating chromatographic methods for the quantitative and qualitative analysis of compounds in various matrices, including environmental samples, pharmaceutical formulations, and biological fluids.
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Demonstrated skills in troubleshooting chromatographic issues, such as peak tailing, ghosting, and coelution, to ensure accurate and reliable results.
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Experience in hyphenated techniques, such as GC-MS and LC-MS, for comprehensive analysis of compounds, including identification of unknown compounds and elucidation of their structures.
Mass Spectrometry
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Extensive experience in mass spectrometry, including quadrupole mass spectrometry (QMS), time-of-flight mass spectrometry (TOF-MS), and tandem mass spectrometry (MS/MS).
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Proficient in ionization techniques, such as electron impact (EI), chemical ionization (CI), and electrospray ionization (ESI), to optimize the ionization efficiency of different compounds.
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Expertise in data acquisition, processing, and … Read full answer