Sample interview questions: Have you ever conducted research on the development of new analytical methods? What challenges did you face?
Sample answer:
Challenges Faced in Developing New Analytical Methods
- Validation and Rigor: Establishing the accuracy, precision, sensitivity, and specificity of the developed method to ensure reliable and reproducible results.
- Optimization and Sensitivity: Identifying the optimal conditions (e.g., sample preparation, reagent concentrations, instrument parameters) to achieve the desired sensitivity and selectivity.
- Matrix Effects: Accounting for the potential interference of matrix components (e.g., in biological or environmental samples) on the analyte measurement.
- Sample Complexity and Variability: Dealing with real-world samples that exhibit complex and variable characteristics, requiring robust methods that can handle a wide range of analytes and matrix compositions.
- Instrument… Read full answer