Sample interview questions: Can you discuss the role of atomic spectroscopy in the field of biomedical research?
Sample answer:
Atomic spectroscopy plays a crucial role in biomedical research, enabling the following key applications:
Biomolecule Characterization:
* Atomic absorption and emission spectroscopy provide quantitative analysis of elements within biomolecules, such as the metal content of proteins and enzymes.
* Infrared spectroscopy identifies functional groups and conformational changes in biological molecules.
Disease Diagnosis and Treatment:
* Atomic spectroscopy can detect specific elements associated with diseases, facilitating early diagnosis and monitoring. For example, inductively coupled plasma mass spectrometry (ICP-MS) is used for heavy metal toxicity analysis to diagnose conditions like Alzheimer’s disease.
* Laser-induced breakdown spectroscopy (LIBS) offers rapid, non-invasive tissue analysis for real-time detection of cancerous cells during surgery.
Drug Development and Monitoring:
* Atomic spectroscopy assists in drug development by characterizing the molecular structure and interactions of new compounds.
* Inductively coupled plasma optical emission spectrometry (ICP-OES) quantifies the elemental composition of drug formulations, ensuring purity and dosage accuracy.
In Vivo Imaging:
* Atomic spectroscopy enables the devel… Read full answer
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