What is your approach to investigating out-of-control (OOC) results or process deviations in pharmaceutical manufacturing?

Sample interview questions: What is your approach to investigating out-of-control (OOC) results or process deviations in pharmaceutical manufacturing?

Sample answer:

Approach to Investigating Out-of-Control (OOC) Results or Process Deviations in Pharmaceutical Manufacturing:

  • Establish a multidisciplinary team: Involve experts from quality control, manufacturing, engineering, and regulatory affairs to provide diverse perspectives and expertise.

  • Collect and review data: Gather all relevant data, including process parameters, product specifications, analytical results, and operator logs. Review the data thoroughly to identify potential trends or anomalies.

  • Identify root causes: Use statistical tools and risk assessment techniques to determine the underlying causes of the deviation. Consider all potential factors, such as raw material impurities, equipment malfunctions, operator error, or environmental conditions.

  • Develop and implement corrective actions: Based on the identified root causes, develop and implement specific corrective actions to mitigate the deviation and prevent recurrence. Ensure the actions are scientifically sound, address the sp… Read full answer

    Source: https://hireabo.com/job/5_2_16/Pharmaceutical%20Chemist

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