Sample interview questions: How do you evaluate the potential risks of exposure to nanomaterials or engineered nanoparticles?
Sample answer:
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Thoroughly characterize the nanomaterial or engineered nanoparticle. Determine its physicochemical properties, such as size, shape, surface charge, and chemical composition. Understanding these properties can provide insights into potential risks and allow for proper categorization and comparison.
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Examine the interaction of the nanomaterial with biological systems. Assess its uptake, distribution, metabolism, and excretion. Investigate potential interactions with biomolecules, cellular components, and tissues. In vitro and in vivo studies can be employed to gain a comprehensive understanding of the nanomaterial’s biological fate and toxicity.
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Conduct toxicological studies to evaluate potential adverse effects. Acute and chronic toxicity studies, genotoxicity assays, reproductive and developmental toxicity studies, and carcinogenicity studies are commonly employed to assess the potential health risks associated with nanomaterial exposure. Both in vitro and in vivo studies are essential for a thorough evaluation.
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Evaluate the potential for environmental fate and transport. Investigate the behavior of the nanomaterial in the environment, including… Read full answer