Sample interview questions: Have you ever worked on a project involving the development of diagnostic assays or devices? If so, please provide details.
Sample answer:
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Project 1: Developed a diagnostic assay for the early detection of breast cancer using circulating tumor cells (CTCs).
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Utilized cutting-edge microfluidic technology to isolate CTCs from patient blood samples.
- Employed molecular techniques, including PCR and next-generation sequencing, to analyze genetic aberrations associated with breast cancer in captured CTCs.
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The assay demonstrated high sensitivity and specificity for detecting breast cancer at an early stage, allowing for timely intervention and improved patient outcomes.
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Project 2: Designed and fabricated a portable diagnostic device for rapid detection of infectious diseases in resource-limited settings.
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Integrated microfluidics, optics, and electronics to create a compact and user-friendly device.
- The device utilized isothermal amplification techniques, such as LAMP, to amplify target DNA or RNA sequences from clinical samples.
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The amplified products were detected using fluorescence-based readouts, enabling rapid and accurate diagnosis of infectious diseases, such as malaria, within a short timeframe.
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Project 3: … Read full answer